Marijuana may increase the risk of bleeding when taken with drugs that increase the risk of bleeding. Some examples include aspirin, anticoagulants (blood thinners), such as warfarin or heparin, anti-platelet drugs such as clopidogrel, and NSAIDS, like ibuprofen or naproxen.
Marijuana may interfere with the way the body processes certain drugs using the liver’s cytochrome P450 enzyme system. As a result, the levels of these drugs may be increased in the blood and may cause increased effects or potentially serious adverse reactions.
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